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Biological Implications of Dioxins/Furans Bioaccumulation in Ecosystems

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Environmental Pollution and Remediation

Part of the book series: Environmental and Microbial Biotechnology ((EMB))

Abstract

Dioxins and furans are a class of persistent, bioaccumulative and toxic organic pollutants in the environment that have garnered attention within the scientific community. This chapter encompasses the bioaccumulation of dioxins/furans in the ecosystem. Further, information on the source and exposure of dioxins/furans is discussed. In addition, the presence of dioxins/furans in the global environment and its regulatory responses are also presented. Persistent dioxins/furans undergo bioaccumulative and biomagnification in the food chain and led to metabolic transformations in human. A detailed compilation of health effects in humans is also elaborated.

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References

  • Ames J, Warner M, Siracusa C, Signorini S, Brambilla P, Mocarelli P, Eskenazi B (2019) Prenatal dioxin exposure and neuropsychological functioning in the Seveso Second Generation Health Study. Int J Hyg Environ Health 222(3):425–433

    Article  CAS  Google Scholar 

  • Assefa A, Tysklind M, Bignert A, Josefsson S, Wiberg K (2019) Sources of polychlorinated dibenzo-p-dioxins and dibenzofurans to Baltic Sea herring. Chemosphere 218:493–500

    Article  CAS  Google Scholar 

  • Bartalini A, Muñoz-Arnanz J, Marsili L, Mazzariol S, Fossi MC, Jiménez B (2019) Evaluation of PCDD/Fs, dioxin-like PCBs and PBDEs in sperm whales from the Mediterranean Sea. Sci Total Environ 653:1417–1425

    Article  CAS  Google Scholar 

  • Boda H, Nghi TN, Nishijo M, Thao PN, Tai PT, Van Luong H, Anh TH, Morikawa Y, Nishino Y, Nishijo H (2018) Prenatal dioxin exposure estimated from dioxins in breast milk and sex hormone levels in umbilical cord blood in Vietnamese newborn infants. Sci Total Environ 615:1312–1318

    Article  CAS  Google Scholar 

  • Bruce-Vanderpuije P, Megson D, Jobst K, Jones GR, Reiner E, Sandau CD, Clarke E, Adu-Kumi S, Gardella JA Jr (2019) Background levels of dioxin-like polychlorinated biphenyls (dlPCBs), polychlorinated, polybrominated and mixed halogenated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs, PBDD/Fs & PXDD/Fs) in sera of pregnant women in Accra, Ghana. Sci Total Environ 673:631–642

    Article  CAS  Google Scholar 

  • Burns CJ, Collins JJ, Budinsky RA, Bodner K, Wilken M, Rowlands JC, Martin GD, Carson ML (2008) Factors related to dioxin and furan body levels among Michigan workers. Environ Res 106(2):250–256

    Article  CAS  Google Scholar 

  • Chirollo C, Ceruso M, Pepe T, Vassallo A, Marrone R, Severino L, Anastasio A (2018) Levels and congeners distribution of dioxins, furans and dioxin-like PCBs in buffaloes adipose tissues sampled in vivo and milk. CyTA-J Food 16(1):1109–1114

    Article  CAS  Google Scholar 

  • Cockerham LG, Young AL (1983) Ultrastructural comparison of liver tissues from field and laboratory TCDD-exposed beach mice. In: Human and environmental risks of chlorinated dioxins and related compounds. Springer, Boston, pp 373–389

    Chapter  Google Scholar 

  • Conesa JA, Ortuño N, Abad E, Rivera-Austrui J (2016) Emissions of PCDD/Fs, PBDD/Fs, dioxin like-PCBs and PAHs from a cement plant using a long-term monitoring system. Sci Total Environ 571:435–443

    Article  CAS  Google Scholar 

  • Danjou AMN, Coudon T, Praud D, Lévêque E, Faure E, Salizzoni P, Le Romancer M, Severi G, Mancini FR, Leffondré K, Dossus L (2019) Long-term airborne dioxin exposure and breast cancer risk in a case-control study nested within the French E3N prospective cohort. Environ Int 124:236–248

    Article  CAS  Google Scholar 

  • Di Meo GP, Perucatti A, Genualdo V, Caputi-Jambrenghi A, Rasero R, Nebbia C, Iannuzzi L (2010) Chromosome fragility in dairy cows exposed to dioxins and dioxin-like PCBs. Mutagenesis 26(2):269–272

    Article  CAS  Google Scholar 

  • Egeland GM, Sweeney MH, Fingerhut MA, Wille KK, Schnorr TM, Halperin WE (1994) Total serum testosterone and gonadotropins in workers exposed to dioxin. Am J Epidemiol 139(3):272–281

    Article  CAS  Google Scholar 

  • EPA US (1999) National air toxics program: the integrated urban strategy. Fed Regist 64:38705–38740

    Google Scholar 

  • Faqi AS, Dalsenter PR, Merker HJ, Chahoud I (1998) Reproductive toxicity and tissue concentrations of low doses of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in male offspring rats exposed throughout pregnancy and lactation. Toxicol Appl Pharmacol 150(2):383–392

    Article  CAS  Google Scholar 

  • Fonnum F, Mariussen E (2009) Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants. J Neurochem 111(6):1327–1347

    Article  CAS  Google Scholar 

  • Foster WG, Maharaj-Briceño S, Cyr DG (2009) Dioxin-induced changes in epididymal sperm count and spermatogenesis. Environ Health Perspect 118(4):458–464

    Article  CAS  Google Scholar 

  • Fujisawa N, Tohyama C, Yoshioka W (2019) Cardiotoxicity induced by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin exposure through lactation in mice. J Toxicol Sci 44(7):505–513

    Article  CAS  Google Scholar 

  • Garner AJ, Pagano JJ (2019) Trends of polychlorinated dioxins, polychlorinated furans, and dioxin-like polychlorinated biphenyls in Chinook and Coho salmonid eggs from a Great Lakes tributary. Environ Pollut 247:1039–1045

    Article  CAS  Google Scholar 

  • Genualdo V, Perucatti A, Iannuzzi A, Di Meo GP, Spagnuolo SM, Caputi-Jambrenghi A, Coletta A, Vonghia G, Iannuzzi L (2012) Chromosome fragility in river buffalo cows exposed to dioxins. J Appl Genet 53(2):221–226

    Article  CAS  Google Scholar 

  • González N, Marquès M, Nadal M, Domingo JL (2018) Levels of PCDD/Fs in foodstuffs in Tarragona County (Catalonia, Spain): Spectacular decrease in the dietary intake of PCDD/Fs in the last 20 years. Food Chem Toxicol 121:109–114

    Article  CAS  Google Scholar 

  • Gou YY, Que DE, Chuang CY, Chao HR, Shy CG, Hsu YC, Lin CW, Chuang KP, Tsai CC, Tayo LL (2016) Dust levels of polybrominated diphenyl ethers (PBDEs) and polybrominated dibenzo-p-dioxins/furans (PBDD/Fs) in the Taiwanese elementary school classrooms: assessment of the risk to school-age children. Sci Total Environ 572:734–741

    Article  CAS  Google Scholar 

  • Gray LE Jr, Ostby JS, Kelce WR (1997a) A dose–response analysis of the reproductive effects of a single gestational dose of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in male Long Evans Hooded rat offspring. Toxicol Appl Pharmacol 146(1):11–20

    Article  CAS  Google Scholar 

  • Gray LE Jr, Wolf C, Mann P, Ostby JS (1997b) In uteroexposure to low doses of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin alters reproductive development of female Long Evans hooded rat offspring. Toxicol Appl Pharmacol 146(2):237–244

    Article  CAS  Google Scholar 

  • Hale MD, Bertucci EM, Rainwater TR, Wilkinson PM, Parrott BB (2019) The impact of maternally derived dioxins on embryonic development and hepatic AHR signaling in a long-lived apex predator. Chemosphere 229:489–499

    Article  CAS  Google Scholar 

  • Hamm JT, Sparrow BR, Wolf D, Birnbaum LS (2000) In utero and lactational exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin alters postnatal development of seminal vesicle epithelium. Toxicol Sci 54(2):424–430

    Article  CAS  Google Scholar 

  • Henríquez-Hernández LA, Luzardo OP, Zumbado M, Serra-Majem L, Valerón PF, Camacho M, Álvarez-Pérez J, Salas-Salvadó J, Boada LD (2017) Determinants of increasing serum POPs in a population at high risk for cardiovascular disease. Results from the PREDIMED-CANARIAS study. Environ Res 156:477–484

    Article  CAS  Google Scholar 

  • Hryhorczuk DO, Withrow WA, Hesse CS, Beasley VR (1981) A wire reclamation incinerator as a source of environmental contamination with tetrachlorodibenzo-p-dioxins and tetrachlorodibenzofurans. Arch Environ Health Int J 36(5):228–234

    Article  CAS  Google Scholar 

  • Hsu YC, Que DE, Gou YY, Tsou TC, Liu CK, Wang YL, Hou WC, Lin YH, Liu WY, Chao HR, Lee WJ (2018) National surveillance of 2, 3, 7, 8-substituted polychlorinated dibenzo-p-dioxins/furans in soil in Taiwan. Chemosphere 203:239–252

    Article  CAS  Google Scholar 

  • Hu J, Wu J, Xu C, Zha X, Hua Y, Yang L, Jin J (2019) Preliminary investigation of polychlorinated dibenzo-p-dioxin and dibenzofuran, polychlorinated naphthalene, and dioxin-like polychlorinated biphenyl concentrations in ambient air in an industrial park at the northeastern edge of the Tibet–Qinghai Plateau, China. Sci Total Environ 648:935–942

    Article  CAS  Google Scholar 

  • Karstensen KH (2008) Formation, release and control of dioxins in cement kilns. Chemosphere 70(4):543–560

    Article  CAS  Google Scholar 

  • Kopf PG, Walker MK (2009) Overview of developmental heart defects by dioxins, PCBs, and pesticides. J Environ Sci Health C 27(4):276–285

    Article  CAS  Google Scholar 

  • Kulkarni PS, Crespo JG, Afonso CA (2008) Dioxins sources and current remediation technologies-a review. Environ Int 34(1):139–153

    Article  CAS  Google Scholar 

  • Kuratsune M, Yoshimura T, Matsuzaka J, Yamaguchi A (1971) Yusho, a poisoning caused by rice oil contaminated with polychlorinated biphenyls. HSMHA Health Rep 86(12):1083

    Article  CAS  Google Scholar 

  • Li XD, Yan M, Chen T, Lu SY, Yan JH, Cen KF (2010) Levels of PCDD/Fs in soil in the vicinity of a medical waste incinerator in China: The temporal variation during 2007–2009. J Hazard Mater 179(1–3):783–789

    Article  CAS  Google Scholar 

  • Mably TA, Bjerke DL, Moore RW, Gendron-Fitzpatrick A, Peterson RE (1992a) In utero and lactational exposure of male rats to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin: 3. Effects on spermatogenesis and reproductive capability. Toxicol Appl Pharmacol 114(1):118–126

    Article  CAS  Google Scholar 

  • Mably TA, Moore RW, Goy RW, Peterson RE (1992b) In utero and lactational exposure of male rats to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin: 2. Effects on sexual behavior and the regulation of luteinizing hormone secretion in adulthood. Toxicol Appl Pharmacol 114(1):108–117

    Article  CAS  Google Scholar 

  • Manikkam M, Tracey R, Guerrero-Bosagna C, Skinner MK (2012) Dioxin (TCDD) induces epigenetic transgenerational inheritance of adult onset disease and sperm epimutations. PLoS One 7(9):e46249

    Article  CAS  Google Scholar 

  • Matta EJ (2018) Pollution in the Uruguay-Argentina border: critical data analysis from two rivers and the pulp mill effluent. Int J Environ Health 9(1):84–109

    Article  Google Scholar 

  • Metelkova L, Zhakovskaya Z, Kukhareva G, Rybalko A, Nikiforov V (2019) Occurrence of PCDD/PCDFs, dioxin-like PCBs, and PBDEs in surface sediments from the Neva River and the Eastern Gulf of Finland (Russia). Environ Sci Pollut Res 26(8):7375–7389

    Article  CAS  Google Scholar 

  • Michalek JE, Rahe AJ, Boyle CA (1998) Paternal dioxin, preterm birth, intrauterine growth retardation, and infant death. Epidemiology 9:161–167

    Article  CAS  Google Scholar 

  • Mukerjee D (1998) Health impact of polychlorinated dibenzo-p-dioxins: a critical review. J Air Waste Manage Assoc 48(2):157–165

    Article  CAS  Google Scholar 

  • Nguyen HM, Tu BM, Watanabe M, Kunisue T, Monirith I, Tanabe S, Sakai S, Subramanian A, Sasikumar K, Pham HV, Bui CT (2003) Open dumping site in Asian developing countries: a potential source of polychlorinated dibenz-p-dioxins and polychlorinated dibenzofurans. Environ Sci Technol 37(8):1493–1502

    Article  CAS  Google Scholar 

  • Ortuño N, Lundstedt S, Lundin L (2015) Emissions of PBDD/Fs, PCDD/Fs and PBDEs from flame-retarded high-impact polystyrene under thermal stress. Chemosphere 123:64–70

    Article  CAS  Google Scholar 

  • Pemberthy D, Quintero A, Martrat MG, Parera J, Ábalos M, Abad E, Villa AL (2016) Polychlorinated dibenzo-p-dioxins, dibenzofurans and dioxin-like PCBs in commercialized food products from Colombia. Sci Total Environ 568:1185–1191

    Article  CAS  Google Scholar 

  • Pereg D, Tampal N, Espandiari P, Robertson LW (2001) Distribution and macromolecular binding of benzo [a] pyrene and two polychlorinated biphenyl congeners in female mice. Chem Biol Interact 137(3):243–258

    Article  CAS  Google Scholar 

  • Perucatti A, Di Meo GP, Albarella S, Ciotola F, Incarnato D, Jambrenghi AC, Peretti V, Vonghia G, Iannuzzi L (2006) Increased frequencies of both chromosome abnormalities and SCEs in two sheep flocks exposed to high dioxin levels during pasturage. Mutagenesis 21(1):67–75

    Article  CAS  Google Scholar 

  • Piskorska-Pliszczynska J, Maszewski S, Mikolajczyk S, Pajurek M, Strucinski P, Olszowy M (2017) Elimination of dioxins in milk by dairy cows after the long-term intake of contaminated sugar beet pellets. Food Addit Contam Part A 34(5):842–852

    CAS  Google Scholar 

  • Psomopoulos CS, Bourka A, Themelis NJ (2009) Waste-to-energy: A review of the status and benefits in USA. Waste Manag 29(5):1718–1724

    Article  CAS  Google Scholar 

  • Quina MJ, Bordado JC, Quinta-Ferreira RM (2011) Air pollution control in municipal solid waste incinerators. The impact of air pollution on health, economy, environment and agricultural sources, pp 331–358

    Google Scholar 

  • Rahman MM, Shon ZH, Ma CJ, Brown RJC, Pandey SK, Park CG, Bae IS, Sohn JR, Yoon HO, Kim KH (2014) Partitioning of dioxins (PCDDs/Fs) in ambient air at urban residential locations. Int J Environ Sci Technol 11(7):1897–1910

    Article  CAS  Google Scholar 

  • Rawn DF, Sadler AR, Casey VA, Breton F, Sun WF, Arbuckle TE, Fraser WD (2017) Dioxins/furans and PCBs in Canadian human milk: 2008–2011. Sci Total Environ 595:269–278

    Article  CAS  Google Scholar 

  • Rehman H, Ullah I, David M, Ullah A, Jahan S (2019) Neonatal exposure to furan alters the development of reproductive systems in adult male Sprague Dawley rats. Food Chem Toxicol 130:231–241

    Article  CAS  Google Scholar 

  • Ren Z, Zheng M (2009) Impacts of human activities on dioxins emissions at national scale. Chemosphere 76(6):853–859

    Article  CAS  Google Scholar 

  • Rezaei E, Farahani A, Buekens A, Chen T, Lu SY, Habibinejad M, Damercheli F, Moghadam SA, Gandomkar M, Bahmani A (2013) Dioxins and furans releases in Iranian mineral industries. Chemosphere 91(6):838–843

    Article  CAS  Google Scholar 

  • Rivera-Austrui J, Martínez K, Marco-Almagro L, Ábalos M, Abad E (2014) Long-term sampling of dioxin-like substances from a clinker kiln stack using alternative fuels. Sci Total Environ 485:528–533

    Article  CAS  Google Scholar 

  • Roberts SM, Lowney YW, Stuchal LD (2019) Bioaccessibility of polychlorinated dioxins and furans in soil from a Superfund site. Chemosphere 214:418–423

    Article  CAS  Google Scholar 

  • Rogan WJ, Gladen BC, Hung KL, Koong SL, Shih LY, Taylor JS, Wu YC, Yang D, Ragan NB, Hsu CC (1988) Congenital poisoning by polychlorinated biphenyls and their contaminants in Taiwan. Science 241(4863):334–336

    Article  CAS  Google Scholar 

  • Schuhmacher M, Mari M, Nadal M, Domingo JL (2019) Concentrations of dioxins and furans in breast milk of women living near a hazardous waste incinerator in Catalonia, Spain. Environ Int 125:334–341

    Article  CAS  Google Scholar 

  • Senthil Kumar K, Kannan K, Paramasivan ON, Shanmuga Sundaram VP, Nakanishi J, Masunaga S (2001) Polychlorinated dibenzo-p-dioxins, dibenzofurans, and polychlorinated biphenyls in human tissues, meat, fish, and wildlife samples from India. Environ Sci Technol 35(17):3448–3455

    Article  CAS  Google Scholar 

  • Silveira LTR, de Mello Santos T, Camora LF, Pinho CF, Anselmo-Franci JA, Domeniconi RF, Justulin LA, Barbisan LF, Scarano WR (2019) Protective effect of resveratrol on urogenital sinus and prostate development in rats exposed in utero to TCDD (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin). Reprod Toxicol 83:82–92

    Article  CAS  Google Scholar 

  • Thackaberry EA, Nunez BA, Ivnitski-Steele ID, Friggins M, Walker MK (2005) Effect of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on murine heart development: alteration in fetal and postnatal cardiac growth, and postnatal cardiac chronotropy. Toxicol Sci 88(1):242–249

    Article  CAS  Google Scholar 

  • Thompson GB, Chapman JC, Richardson BJ (1992) Disposal of hazardous wastes in Australia: implications for marine pollution. Mar Pollut Bull 25(5–8):155–162

    Article  CAS  Google Scholar 

  • Tsukimori K, Uchi H, Mitoma C, Yasukawa F, Chiba T, Todaka T, Hirata T, Fukushima K, Wake N (2012) Maternal exposure to high levels of dioxins in relation to birth weight in women affected by Yusho disease. Environ Int 38(1):79–86

    Article  CAS  Google Scholar 

  • Ueno D, Watanabe M, Subramanian A, Tanaka H, Fillmann G, Lam PK, Zheng GJ, Muchtar M, Razak H, Prudente M, Chung KH (2005) Global pollution monitoring of polychlorinated dibenzo-p-dioxins (PCDDs), furans (PCDFs) and coplanar polychlorinated biphenyls (coplanar PCBs) using skipjack tuna as bioindicator. Environ Pollut 136(2):303–313

    Article  CAS  Google Scholar 

  • Van den Berg M, Birnbaum LS, Denison M, De Vito M, Farland W, Feeley M, Fiedler H, Hakansson H, Hanberg A, Haws L, Rose M (2006) The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 93(2):223–241

    Article  CAS  Google Scholar 

  • Wang LC, Hsi HC, Wang YF, Lin SL, Chang-Chien GP (2010) Distribution of polybrominated diphenyl ethers (PBDEs) and polybrominated dibenzo-p-dioxins and dibenzofurans (PBDD/Fs) in municipal solid waste incinerators. Environ Pollut 158(5):1595–1602

    Article  CAS  Google Scholar 

  • Wang X, Ni Y, Zhang H, Zhang X, Chen J (2012) Formation and emission of PCDD/Fs in Chinese non-wood pulp and paper mills. Environ Sci Technol 46(21):12234–12240

    Google Scholar 

  • Wesselink A, Warner M, Samuels S, Parigi A, Brambilla P, Mocarelli P, Eskenazi B (2014) Maternal dioxin exposure and pregnancy outcomes over 30 years of follow-up in Seveso. Environ Int 63:143–148

    Article  CAS  Google Scholar 

  • Wimmerová S, van den Berg M, Chovancová J, Patayová H, Jusko TA, van Duursen MB, Murínová ĽP, Canton RF, van Ede KI, Trnovec T (2016) Relative effect potency estimates of dioxin-like activity for dioxins, furans, and dioxin-like PCBs in adults based on cytochrome P450 1A1 and 1B1 gene expression in blood. Environ Int 96:24–33

    Article  CAS  Google Scholar 

  • Xu J, Ye Y, Huang F, Chen H, Wu H, Huang J, Hu J, Xia D, Wu Y (2016) Association between dioxin and cancer incidence and mortality: a meta-analysis. Sci Rep 6:38012

    Article  CAS  Google Scholar 

  • Yang L, Liu G, Zhu Q, Zheng M (2019) Small-scale waste incinerators in rural China: Potential risks of dioxin and polychlorinated naphthalene emissions. Emerg Contam 5:31–34

    Article  Google Scholar 

  • Young AL, Thalken CE, Arnold EL, Cupello JM, Cockerham LG (1976) Fate of 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) in the environment: summary and decontamination recommendations (No. USAFA-TR-76-18). USAF Academy Colorado Springs

    Google Scholar 

  • Zhou S, Zhu H, Huang S, Zhou J, Zhang S, Wang C (2019) Biomagnification and risk assessment of polychlorinated biphenyls in food web components from Zhoushan fishing ground, China. Mar Pollut Bull 142:613–619

    Article  CAS  Google Scholar 

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Acknowledgements

Authors thank Prof. M. Sivanandham, Secretary, SVEHT and SVCE Management for their support and encouragement.

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Authors and Affiliations

  1. Department of Biotechnology, Sri Venkateswara College of Engineering (Autonomous), Sriperumbudur Tk, Tamil Nadu, India

    Jose Gnanaleela Aswin Jeno, Ravichandran Rathna & Ekambaram Nakkeeran

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  1. Jose Gnanaleela Aswin Jeno
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  2. Ravichandran Rathna
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  3. Ekambaram Nakkeeran
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Correspondence to Ekambaram Nakkeeran .

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  1. Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar, India

    Ram Prasad

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Jeno, J.G.A., Rathna, R., Nakkeeran, E. (2021). Biological Implications of Dioxins/Furans Bioaccumulation in Ecosystems. In: Prasad, R. (eds) Environmental Pollution and Remediation. Environmental and Microbial Biotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-15-5499-5_14

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